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Administration of PPA@aPD-L1 to mouse models has remodelled the immunosuppressive landscape, characterised by increased CD8 + T cell infiltration and decreased Treg cell infiltration, through the inhibition of the NF-B and STAT3 pathways in tumour cells, compared to PPA or aPD-L1 alone [172]

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Synergistic interactions of indole-2-carboxamides and -lactam antibiotics against Mycobacterium abscessus